I recently noticed that there are SATA drives available which have 4,096 (4K) byte block size. Will the STB Suite work with these new drives?

You bet it will!

The STB Suite is what we call “block size agnostic” – we don’t care what the block size is. For each drive, we ask it for its capacity – its block size and the number of blocks it has.

We then use that block size in all of our calculations and I/O.

So the good answer is “yes- the STB Suite will work with drives of any and all block sizes”

Here is a screenshot of a current 12G SAS drive which uses 4K blocks –